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PSMD2 antibody

PSMD2 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855347
  • Target See all PSMD2 Antibodies
    PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))
    Reactivity
    • 54
    • 14
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 9
    • 1
    Rabbit
    Clonality
    • 47
    • 7
    Polyclonal
    Conjugate
    • 34
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMD2 antibody is un-conjugated
    Application
    • 41
    • 28
    • 14
    • 11
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to PSMD2 (26S proteasome non-ATPase regulatory subunit 2)
    PSMD2 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human PSMD2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PSMD2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: JC , BCL-1 , A431

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.82 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))
    Alternative Name
    proteasome 26S subunit, non-ATPase 2 (PSMD2 Products)
    Synonyms
    DDBDRAFT_0192101 antibody, DDBDRAFT_0232978 antibody, DDB_0192101 antibody, DDB_0232978 antibody, zgc:65921 antibody, MGC83233 antibody, psmd2 antibody, MGC97650 antibody, PSMD2 antibody, P97 antibody, RPN1 antibody, S2 antibody, TRAP2 antibody, 9430095H01Rik antibody, AA407121 antibody, TEG-190 antibody, Tex190 antibody, 26S proteasome non-ATPase regulatory subunit 2 antibody, 26S proteasome regulatory subunit S2 antibody, proteasome 26S subunit, non-ATPase 2 antibody, proteasome 26S subunit, non-ATPase 2 L homeolog antibody, proteasome 26S subunit, non-ATPase 2 S homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 antibody, psmD2 antibody, NAEGRDRAFT_83014 antibody, DICPUDRAFT_55026 antibody, psmd2 antibody, psmd2.L antibody, psmd2.S antibody, PSMD2 antibody, Psmd2 antibody
    Background
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.

    Molecular Weight
    100 kDa
    Gene ID
    5708
    UniProt
    Q13200
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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