PDCD6 antibody

Catalog No. ABIN2855317

Product Details anti-PDCD6 Antibody

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to PDCD6 (programmed cell death 6)
PDCD6 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PDCD6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa nucleus

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.62 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Alternative Name: programmed cell death 6 (PDCD6 Products)

Synonyms: pdcd6 antibody, MGC52821 antibody, MGC132114 antibody, zgc:63952 antibody, PDCD6 antibody, ALG-2 antibody, PEF1B antibody, AV299538 antibody, Alg2 antibody, MA-3 antibody, PS2 antibody, alg-2 antibody, programmed cell death 6 L homeolog antibody, programmed cell death 6 antibody, pdcd6.L antibody, pdcd6 antibody, PDCD6 antibody, Pdcd6 antibody

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.

Cellular Localization: Nucleus membrane, Peripheral membrane protein , Endoplasmic reticulum membrane, Peripheral membrane protein , Nucleus

Molecular Weight: 22 kDa

Gene ID: 10016

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity