APOBEC3C antibody (Center)

Catalog No. ABIN2855306

Product Details anti-APOBEC3C Antibody

Target: APOBEC3C (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBEC3C antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Rabbit Polyclonal antibody to APOBEC3C (probable DNA dC->dU-editing enzyme APOBEC-3C)
APOBEC3C antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human APOBEC3C. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: NCI-H929

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-APOBEC3C antibody (ABIN2855306)

Kawamura, Sanchez Calle, Yamamoto, Sato, Ochiya: "Extracellular vesicles mediate the horizontal transfer of an active LINE-1 retrotransposon." in: Journal of extracellular vesicles, Vol. 8, Issue 1, pp. 1643214, (2019) (PubMed).

Kim, Kwon, Lee, Verma, Rudra, Kim, Kang, Nam, Kim, Im: "Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness." in: Oncogenesis, Vol. 7, Issue 11, pp. 91, (2018) (PubMed).

Target Details for APOBEC3C

Target: APOBEC3C (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C))

Alternative Name: APOBEC3C (APOBEC3C Products)

Synonyms: APOBEC3C antibody, A3C antibody, APOBEC1L antibody, ARDC2 antibody, ARDC4 antibody, ARP5 antibody, PBI antibody, bK150C2.3 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3C antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C antibody, APOBEC3C antibody

Background: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.

Molecular Weight: 23 kDa

Gene ID: 27350