KARS antibody
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- Target See all KARS Antibodies
- KARS (Lysyl-tRNA Synthetase (KARS))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KARS antibody is un-conjugated
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse
- Characteristics
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Rabbit Polyclonal antibody to Lysyl-tRNA synthetase (lysyl-tRNA synthetase)
Lysyl-tRNA synthetase antibody - Purification
- Affinity purified by Protein A.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Lysyl-tRNA synthetase. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product KARS Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: H1299
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- KARS (Lysyl-tRNA Synthetase (KARS))
- Alternative Name
- lysyl-tRNA synthetase (KARS Products)
- Background
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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Cytoplasm - Molecular Weight
- 68 kDa
- Gene ID
- 3735
- UniProt
- Q15046
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