EIF3I antibody

Catalog No. ABIN2855240

Product Details anti-EIF3I Antibody

Target: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3I antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to EIF3 beta (eukaryotic translation initiation factor 3, subunit I)
EIF3 beta antibody [N2C3]

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the center region of human EIF3 beta. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for EIF3I

Target: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Alternative Name: eukaryotic translation initiation factor 3 subunit I (EIF3I Products)

Synonyms: EIF3S2 antibody, PRO2242 antibody, TRIP-1 antibody, TRIP1 antibody, eIF3-beta antibody, eIF3-p36 antibody, 36kDa antibody, D4Ertd632e antibody, Eif3s2 antibody, Trip1 antibody, eIF-3-beta antibody, eIF3 p36 antibody, eif3s2 antibody, hm:zehn0464 antibody, wu:fb62b08 antibody, zgc:56211 antibody, zgc:77823 antibody, CaO19.2967 antibody, eIF-3 39 kDa subunit homolog antibody, eIF3i antibody, eif3-beta antibody, eif3-p36 antibody, eif3i antibody, pro2242 antibody, trip-1 antibody, trip1 antibody, eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit I antibody, Eukaryotic Initiation Factor antibody, Eukaryotic translation initiation factor 3 subunit I antibody, translation initiation factor eIF3 subunit i antibody, eukaryotic translation initiation factor 3 subunit I L homeolog antibody, EIF3I antibody, Eif3i antibody, eif-3.I antibody, eIF3i antibody, eif3i antibody, TIF34 antibody, eif3i.L antibody

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Molecular Weight: 37 kDa

Gene ID: 8668

UniProt: Q13347

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA