SRP14 antibody

Catalog No. ABIN2855206

Product Details anti-SRP14 Antibody

Target: SRP14 (Signal Recognition Particle 14kDa (Homologous Alu RNA Binding Protein) (SRP14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP14 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to SRP14 (signal recognition particle 14 kDa (homologous Alu RNA binding protein))
SRP14 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human SRP14. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.73 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SRP14

Target: SRP14 (Signal Recognition Particle 14kDa (Homologous Alu RNA Binding Protein) (SRP14))

Alternative Name: signal recognition particle 14 (SRP14 Products)

Synonyms: zgc:112290 antibody, 14kDa antibody, AW536328 antibody, ALURBP antibody, signal recognition particle 14 antibody, signal recognition particle 14kDa S homeolog antibody, srp14 antibody, Srp14 antibody, srp14.S antibody, SRP14 antibody

Background: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.

Cellular Localization: Cytoplasm

Molecular Weight: 15 kDa

Gene ID: 6727

UniProt: P37108