Myosin 9 antibody (N-Term)

Catalog No. ABIN2855153

Product Details anti-Myosin 9 Antibody

Target: Myosin 9 (MYH9)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin 9 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Specificity: This antibody may cross react with MYH10, MYH14, or other family members.

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to MYH9 (myosin, heavy chain 9, non-muscle)
MYH9 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human MYH9. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , NT2D1 , PC-3

Validation: KO/KD, Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.31 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Myosin 9

Target: Myosin 9 (MYH9)

Alternative Name: myosin heavy chain 9 (MYH9 Products)

Synonyms: BDPLT6 antibody, DFNA17 antibody, EPSTS antibody, FTNS antibody, MHA antibody, NMHC-II-A antibody, NMMHC-IIA antibody, NMMHCA antibody, C80049 antibody, D0Jmb2 antibody, E030044M24Rik antibody, Fltn antibody, Myhn-1 antibody, Myhn1 antibody, NMHC II-A antibody, NMHCIIA antibody, NMMHC II-a antibody, NMMHC-A antibody, TU72.6 antibody, fi22c04 antibody, myh9 antibody, myh9l2 antibody, wu:fi22c04 antibody, wu:fj85e11 antibody, zgc:162029 antibody, zgc:66164 antibody, NMMHC antibody, myosin antibody, non-muscle antibody, nonmuscle antibody, KLG/PTK7 antibody, dfna17 antibody, epsts antibody, ftns antibody, nmhc-ii-a antibody, nmmhca antibody, myosin heavy chain 9 antibody, myosin, heavy polypeptide 9, non-muscle antibody, myosin, heavy chain 9a, non-muscle antibody, myosin, heavy chain 9, non-muscle antibody, myosin, heavy chain 9, non-muscle L homeolog antibody, MYH9 antibody, Myh9 antibody, myh9a antibody, myh9.L antibody

Background: This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Molecular Weight: 227 kDa

Gene ID: 4627

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex