EIF4G2 antibody (N-Term)

Catalog No. ABIN2855137

Product Details anti-EIF4G2 Antibody

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4G2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to DAP5 (eukaryotic translation initiation factor 4 gamma, 2)
DAP5 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human DAP5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , Mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for EIF4G2

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Alternative Name: eukaryotic translation initiation factor 4 gamma 2 (EIF4G2 Products)

Synonyms: AAG1 antibody, DAP5 antibody, NAT1 antibody, P97 antibody, NAT1B antibody, eif4g2 antibody, hm:zeh1307 antibody, wu:fa14h01 antibody, wu:fb44h01 antibody, wu:fb59c06 antibody, wu:fc21b05 antibody, EIF4G2 antibody, AA589388 antibody, DAP-5 antibody, E130105L11Rik antibody, Nat1 antibody, Natm1 antibody, p97 antibody, NAT1A antibody, im:7148615 antibody, wu:fb81f07 antibody, wu:fb82b06 antibody, wu:fb98h08 antibody, dap5 antibody, eif4g2.L antibody, nat1 antibody, eukaryotic translation initiation factor 4 gamma 2 antibody, eukaryotic translation initiation factor 4, gamma 2b antibody, eukaryotic translation initiation factor 4, gamma 2 antibody, eukaryotic translation initiation factor 4 gamma, 2 antibody, eIF4G-related protein NAT1 antibody, eukaryotic translation initiation factor 4, gamma 2a antibody, eukaryotic translation initiation factor 4 gamma, 2 S homeolog antibody, EIF4G2 antibody, eif4g2b antibody, Eif4g2 antibody, nat1 antibody, eif4g2a antibody, eif4g2.S antibody

Background: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Molecular Weight: 102 kDa

Gene ID: 1982

UniProt: P78344