Peroxiredoxin 1 antibody
-
- Target See all Peroxiredoxin 1 (PRDX1) Antibodies
- Peroxiredoxin 1 (PRDX1)
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Peroxiredoxin 1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
-
Rabbit Polyclonal antibody to PRX I (peroxiredoxin 1)
PRX I antibody [N1C2] - Purification
- Affinity purified by Protein A.
- Grade
- KO Validated
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human PRX I. The exact sequence is proprietary.
- Isotype
- IgG
-
-
- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
-
Positive Control: 293T , NIH-3T3
Validation: KO/KD, Orthogonal
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.22 mg/mL
- Buffer
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7), 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Target
- Peroxiredoxin 1 (PRDX1)
- Alternative Name
- peroxiredoxin 1 (PRDX1 Products)
- Background
-
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.
- Molecular Weight
- 22 kDa
- Gene ID
- 5052
- UniProt
- Q06830
- Pathways
- p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
-