Peroxiredoxin 1 antibody

Catalog No. ABIN2855135

Product Details anti-Peroxiredoxin 1 Antibody

Target: Peroxiredoxin 1 (PRDX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to PRX I (peroxiredoxin 1)
PRX I antibody [N1C2]

Purification: Affinity purified by Protein A.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human PRX I. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , NIH-3T3

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.22 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7), 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Alternative Name: peroxiredoxin 1 (PRDX1 Products)

Synonyms: MSP23 antibody, NKEF-A antibody, NKEFA antibody, PAG antibody, PAGA antibody, PAGB antibody, PRX1 antibody, PRXI antibody, TDPX2 antibody, NkefA antibody, OSF-3 antibody, OSF3 antibody, Paga antibody, PrdxI antibody, PrxI antibody, TDX2 antibody, TPxA antibody, Tdpx2 antibody, prx1 antibody, Hbp23 antibody, MGC80194 antibody, MGC84820 antibody, PRDX1 antibody, msp23 antibody, nkefa antibody, pag antibody, paga antibody, pagb antibody, prx-1 antibody, prxi antibody, tdpx2 antibody, hm:zehl0637 antibody, zgc:110343 antibody, TPX-2 antibody, peroxiredoxin 1 antibody, peroxiredoxin 1 S homeolog antibody, peroxiredoxin-1 pseudogene antibody, PRDX1 antibody, Prdx1 antibody, prdx1.S antibody, prdx1 antibody, LOC100350232 antibody

Background: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.

Molecular Weight: 22 kDa

Gene ID: 5052

UniProt: Q06830

Pathways: p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events