CAPZB antibody (Center)

Catalog No. ABIN2855126

Product Details anti-CAPZB Antibody

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Rat (Rattus), Pig (Porcine), Cow (Bovine)

Cross-Reactivity (Details): Rat (100 %), Pig (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to CAPZB (capping protein (actin filament) muscle Z-line, beta)
CAPZB antibody

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CAPZB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: A431 , H1299 , HepG2 , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-CAPZB antibody (ABIN2855126)

Xiong, Zhang, Huang, Liu, Wang, Shi, Li: "Expression pattern of prohibitin, capping actin protein of muscle Z-line beta subunit and tektin-2 gene in Murrah buffalo sperm and its relationship with sperm motility." in: Asian-Australasian journal of animal sciences, Vol. 31, Issue 11, pp. 1729-1737, (2018) (PubMed).

Target Details for CAPZB

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Alternative Name: CAPZB (CAPZB Products)

Synonyms: CAPB antibody, CAPPB antibody, CAPZ antibody, wu:fk65f06 antibody, zgc:66149 antibody, MGC52754 antibody, capzb antibody, 1700120C01Rik antibody, AI325129 antibody, CPB1 antibody, CPB2 antibody, CPbeat2 antibody, CPbeta1 antibody, CPbeta2 antibody, Cappb1 antibody, capping actin protein of muscle Z-line beta subunit antibody, capping protein (actin filament) muscle Z-line, beta antibody, F-actin-capping protein subunit beta antibody, f-actin-capping protein subunit beta antibody, capping protein (actin filament) muscle Z-line, beta L homeolog antibody, CAPZB antibody, capzb antibody, AOR_1_1412174 antibody, MCYG_05913 antibody, VDBG_04956 antibody, MGYG_06053 antibody, PGTG_03178 antibody, Tsp_07516 antibody, capzb.L antibody, Capzb antibody

Background: CAPZB is a member of the F-actin capping protein family. This gene encodes the beta subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments.

Cellular Localization: Cytoplasm , cytoskeleton

Molecular Weight: 31 kDa

Gene ID: 832

Pathways: Regulation of Actin Filament Polymerization