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PSMD8 antibody

PSMD8 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855106
  • Target See all PSMD8 Antibodies
    PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
    Reactivity
    • 35
    • 24
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 3
    Rabbit
    Clonality
    • 35
    • 1
    Polyclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMD8 antibody is un-conjugated
    Application
    • 26
    • 13
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to PSMD8 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 8)
    PSMD8 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human PSMD8. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PSMD8 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: A549

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
    Alternative Name
    proteasome 26S subunit, non-ATPase 8 (PSMD8 Products)
    Synonyms
    HIP6 antibody, HYPF antibody, Nin1p antibody, Rpn12 antibody, S14 antibody, p31 antibody, hip6 antibody, hypf antibody, nin1p antibody, rpn12 antibody, psmd8b antibody, 6720456J22Rik antibody, AA407360 antibody, AL033291 antibody, AL033322 antibody, AL033323 antibody, C76433 antibody, psmd8 antibody, psmd8a antibody, fa93g07 antibody, fb17c09 antibody, fb49a10 antibody, zgc:86762 antibody, wu:fa93g07 antibody, wu:fb17c09 antibody, wu:fb49a10 antibody, PSMD8 antibody, proteasome 26S subunit, non-ATPase 8 antibody, proteasome 26S subunit, non-ATPase 8 S homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 antibody, proteasome 26S subunit, non-ATPase 8 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene antibody, PSMD8 antibody, psmd8.S antibody, Psmd8 antibody, psmd8.L antibody, psmd8 antibody, LOC468490 antibody
    Background
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

    Molecular Weight
    40 kDa
    Gene ID
    5714
    UniProt
    P48556
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Proton Transport, Synthesis of DNA, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
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