ADAR antibody
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- Target See all ADAR Antibodies
- ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ADAR antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Rat
- Characteristics
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Rabbit Polyclonal antibody to ADAR1 (adenosine deaminase, RNA-specific)
ADAR1 antibody [N3C1], Internal - Purification
- Purified by antigen-affinity chromatography.
- Grade
- KO Validated
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ADAR1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product ADAR Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: 293T , A431 , HeLa , HepG2
Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.82 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
- Alternative Name
- adenosine deaminase RNA specific (ADAR Products)
- Background
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This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Cytoplasm , Nucleus , nucleolus - Molecular Weight
- 136 kDa
- Gene ID
- 103
- UniProt
- P55265
- Pathways
- Protein targeting to Nucleus
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