GAP43 antibody

Catalog No. ABIN2855084

Product Details anti-GAP43 Antibody

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAP43 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to GAP43 (growth associated protein 43)
GAP43 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GAP43. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IMR32 , mouse hippocampus , rat hippocampus

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.55 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GAP43

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Alternative Name: growth associated protein 43 (GAP43 Products)

Synonyms: B-50 antibody, PP46 antibody, Basp2 antibody, GAP-43 antibody, b-50 antibody, gap-43 antibody, gap43b antibody, pp46 antibody, cb310 antibody, gap antibody, gap43 antibody, gap43a antibody, growth associated protein 43 antibody, growth associated protein 43 L homeolog antibody, growth associated protein 43 S homeolog antibody, GAP43 antibody, Gap43 antibody, gap43.L antibody, gap43 antibody, gap43.S antibody

Background: The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Cellular Localization: Cell membrane, Peripheral membrane protein, Cytoplasmic side , Cell projection , growth cone membrane, Peripheral membrane protein, Cytoplasmic side , Cell junction , synapse

Molecular Weight: 25 kDa

Gene ID: 2596

UniProt: P17677