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MEF2A antibody (C-Term)

MEF2A Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855000
  • Target See all MEF2A Antibodies
    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
    Binding Specificity
    • 25
    • 22
    • 15
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 124
    • 102
    • 85
    • 10
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 120
    • 6
    Rabbit
    Clonality
    • 110
    • 16
    Polyclonal
    Conjugate
    • 64
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This MEF2A antibody is un-conjugated
    Application
    • 87
    • 37
    • 36
    • 26
    • 26
    • 24
    • 20
    • 12
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to MEF2A (myocyte enhancer factor 2A)
    MEF2A antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human MEF2A. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MEF2A Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: H1299 , PC-12 , Rat-2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
    Alternative Name
    myocyte enhancer factor 2A (MEF2A Products)
    Background
    The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]

    Cellular Localization: Nucleus
    Molecular Weight
    55 kDa
    Gene ID
    4205
    UniProt
    Q02078
    Pathways
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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