DTNBP1 antibody

Catalog No. ABIN2854989

Product Details anti-DTNBP1 Antibody

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to Dysbindin (dystrobrevin binding protein 1)
Dysbindin antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Dysbindin. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1 , PC-3 , U87-MG , SK-N-SH , mouse brain , rat brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DTNBP1

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Alternative Name: dystrobrevin binding protein 1 (DTNBP1 Products)

Synonyms: 5430437B18Rik antibody, AW048963 antibody, Bloc1s8 antibody, dysbindin antibody, sdy antibody, BLOC1S8 antibody, DBND antibody, HPS7 antibody, My031 antibody, SDY antibody, dtnbp1 antibody, zgc:56462 antibody, MGC83903 antibody, dbnd antibody, hps7 antibody, my031 antibody, MGC85477 antibody, DTNBP1 antibody, CG6856 antibody, Ddysb antibody, Dmel\\CG6856 antibody, si:ch211-285p6.1 antibody, dystrobrevin binding protein 1 antibody, Dysbindin antibody, dystrobrevin binding protein 1a antibody, dystrobrevin binding protein 1 L homeolog antibody, dystrobrevin binding protein 1 S homeolog antibody, dystrobrevin binding protein 1b antibody, Dtnbp1 antibody, DTNBP1 antibody, dtbp1 antibody, dtnbp1a antibody, dtnbp1.L antibody, dtnbp1.S antibody, dtnbp1 antibody, Dysb antibody, dtnbp1b antibody

Background: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Cellular Localization: Cytoplasm

Molecular Weight: 39 kDa

Gene ID: 84062

UniProt: Q96EV8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling