RGS6 antibody (C-Term)

Catalog No. ABIN285498

Product Details anti-RGS6 Antibody

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Binding Specificity: C-Term

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This RGS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificity: This monoclonal antibody crossreacts to THC and metabolite. There is no reactivityagainst Opiates, Cocaine Metabolites, Amphetamine or Phencylidine.

Cross-Reactivity (Details): This antibody recognizes human GAP and may crossreact with other species.

Purification: Protein G affinity chromatography

Immunogen: GAP antibody was raised in sheep using human GTPase Activating Protein (C-terminal peptide)-KLH as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Protein G purified and supplied in 150 mM PBS buffer, pH 7.3.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for RGS6

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Alternative Name: GAP (RGS6 Products)

Synonyms: RGS6 antibody, DKFZp459O0734 antibody, GAP antibody, hm:zeh0300 antibody, si:ch211-268e23.2 antibody, regulator of G protein signaling 6 antibody, regulator of G-protein signaling 6 antibody, regulator of G-protein signaling 6 S homeolog antibody, RGS6 antibody, Rgs6 antibody, rgs6.S antibody, rgs6 antibody

Background: GTPase-Activating Proteins, or GAPs, or GTPase-Accelerating Proteins are a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity, with the result of terminating the signaling event. G proteins are switched from the active, GTP-bound form to the inactive, GDP-bound form by hydrolysis of the GTP through intrinsic GTPase-activity.

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling