GALC antibody

Catalog No. ABIN2854965

Product Details anti-GALC Antibody

Target: GALC (Galactosylceramidase (GALC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit polyclonal antibody to Galactosylceramidase (galactosylceramidase)
Galactosylceramidase antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Galactosylceramidase. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation:Orthogonal, Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.46 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GALC

Target: GALC (Galactosylceramidase (GALC))

Alternative Name: galactosylceramidase (GALC Products)

Synonyms: 2310068B06Rik antibody, A930008M05Rik antibody, AW212969 antibody, AW413532 antibody, Gacy antibody, twi antibody, twitcher antibody, galc antibody, galcl antibody, zgc:92561 antibody, si:ch211-199l3.4 antibody, GALCERase antibody, wu:fi04e07 antibody, zgc:56444 antibody, galactosylceramidase antibody, galactosylceramidase a antibody, Galactosylceramidase antibody, galactosylceramidase L homeolog antibody, galactosylceramidase b antibody, GALC antibody, Galc antibody, galca antibody, galc antibody, Caci_7107 antibody, Bacsa_1415 antibody, Spico_0384 antibody, LOC100304802 antibody, galc.L antibody, galcb antibody

Background: This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Cellular Localization: Lysosome

Molecular Weight: 77 kDa

Gene ID: 2581

UniProt: P54803