MEF2A antibody (N-Term)
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- Target See all MEF2A Antibodies
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MEF2A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm))
- Cross-Reactivity
- Human, Zebrafish (Danio rerio)
- Characteristics
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Rabbit polyclonal antibody to MEF2A (myocyte enhancer factor 2A)
MEF2A antibody [N1N2], N-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human MEF2A. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product MEF2A Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Wm: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: HeLa
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.77 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
- Alternative Name
- myocyte enhancer factor 2A (MEF2A Products)
- Synonyms
- ADCAD1 antibody, RSRFC4 antibody, RSRFC9 antibody, mef2 antibody, A430079H05Rik antibody, mef2a antibody, wu:fd19d02 antibody, adcad1 antibody, rsrfc4 antibody, rsrfc9 antibody, sl2 antibody, MEF2A antibody, xmef2a antibody, myocyte enhancer factor 2A antibody, myocyte enhancer factor 2aa antibody, myocyte enhancer factor 2a antibody, myocyte-specific enhancer factor 2A antibody, myocyte-specific enhancer factor 2a, putative antibody, myocyte enhancer factor 2A L homeolog antibody, MEF2A antibody, Mef2a antibody, mef2aa antibody, EDI_092490 antibody, EDI_038250 antibody, Smp_161530 antibody, mef2a.L antibody, mef2a antibody, LOC539054 antibody
- Background
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The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]
Cellular Localization: Nucleus - Molecular Weight
- 55 kDa
- Gene ID
- 4205
- UniProt
- Q02078
- Pathways
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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