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SNRPE antibody (Internal Region)

SNRPE Reactivity: Human, Mouse, Rat WB, IHC (p), IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854894
  • Target See all SNRPE Antibodies
    SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
    Binding Specificity
    • 15
    • 15
    • 10
    • 9
    • 8
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 75
    • 57
    • 54
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 89
    • 1
    Rabbit
    Clonality
    • 90
    Polyclonal
    Conjugate
    • 29
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SNRPE antibody is un-conjugated
    Application
    • 30
    • 30
    • 27
    • 26
    • 13
    • 12
    • 10
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Characteristics
    Rabbit polyclonal antibody to B-Raf (v-raf murine sarcoma viral oncogene homolog B1)
    B-Raf antibody [N2C1], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human B-Raf. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product SNRPE Primary Antibody
  • Application Notes
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:10000*
    Comment

    Positive Control: A549 , H1299 , HCT116 , PC-12

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
    Alternative Name
    B-Raf (SNRPE Products)
    Synonyms
    B-raf antibody, HYPT11 antibody, SME antibody, Sm-E antibody, b-raf antibody, sm-e antibody, sme antibody, SmE antibody, snRNP-E antibody, AL022645 antibody, C76690 antibody, zgc:56682 antibody, small nuclear ribonucleoprotein polypeptide E antibody, small nuclear ribonucleoprotein polypeptide E L homeolog antibody, small nuclear ribonucleoprotein E antibody, SNRPE antibody, snrpe.L antibody, Snrpe antibody, snrpe antibody
    Background
    This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

    Cellular Localization: Cytoplasm
    Molecular Weight
    84 kDa
    Gene ID
    673
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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