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NYS48/HAUS8 antibody

KO Validated HAUS8 Reactivity: Human WB, IF, ICC, IHC (p), IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854852
  • Target See all NYS48/HAUS8 (HAUS8) Antibodies
    NYS48/HAUS8 (HAUS8) (HAUS Augmin-Like Complex, Subunit 8 (HAUS8))
    Reactivity
    • 28
    • 5
    • 2
    • 1
    Human
    Host
    • 27
    • 2
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    This NYS48/HAUS8 antibody is un-conjugated
    Application
    • 27
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to HICE1 (HAUS augmin-like complex, subunit 8)
    HICE1 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein corresponding to human HICE1
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:50-1:500. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: U2OS

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.17 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    NYS48/HAUS8 (HAUS8) (HAUS Augmin-Like Complex, Subunit 8 (HAUS8))
    Alternative Name
    HAUS augmin like complex subunit 8 (HAUS8 Products)
    Synonyms
    2410004L22Rik antibody, Hice1 antibody, NY-SAR-48 antibody, hice1 antibody, DGT4 antibody, HICE1 antibody, Ny-sar-48 antibody, RGD1311565 antibody, 4HAUS augmin-like complex, subunit 8 antibody, HAUS augmin like complex subunit 8 L homeolog antibody, HAUS augmin like complex subunit 8 antibody, HAUS augmin-like complex, subunit 8 antibody, Haus8 antibody, haus8.L antibody, HAUS8 antibody
    Background
    HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220], Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM]

    Cellular Localization: Cytoplasm , Centrosome , Spindle
    Molecular Weight
    45 kDa
    Gene ID
    93323
    UniProt
    Q9BT25
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