ITGA6 antibody (Internal Region)

Catalog No. ABIN2854795

Product Details anti-ITGA6 Antibody

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Cow (Bovine)

Cross-Reactivity (Details): Mouse (94 %), Bovine (94 %)

Characteristics: Rabbit Polyclonal antibody to Integrin alpha 6 (integrin, alpha 6)
Integrin alpha 6 antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Integrin alpha 6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: Human ESC , Rat lung

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.64 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-ITGA6 antibody (ABIN2854795)

Chen, Lin, Tsai, He, Luo, Chiu, Herschman, Li: "Exosomal 2',3'-CNP from mesenchymal stem cells promotes hippocampus CA1 neurogenesis/neuritogenesis and contributes to rescue of cognition/learning deficiencies of damaged brain." in: Stem cells translational medicine, Vol. 9, Issue 4, pp. 499-517, (2020) (PubMed).

Rivera-Serrano, González-López, Das, Lemon: "Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses." in: eLife, Vol. 8, (2019) (PubMed).

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: Integrin alpha 6 (ITGA6 Products)

Background: The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molecular Weight: 127 kDa

Gene ID: 3655

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex