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NPPB antibody

NPPB Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854787
  • Target See all NPPB Antibodies
    NPPB (Natriuretic Peptide Precursor B (NPPB))
    Reactivity
    • 29
    • 3
    • 3
    • 3
    • 2
    Human
    Host
    • 23
    • 14
    • 1
    Rabbit
    Clonality
    • 23
    • 15
    Polyclonal
    Conjugate
    • 24
    • 8
    • 5
    • 1
    This NPPB antibody is un-conjugated
    Application
    • 27
    • 27
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to BNP (natriuretic peptide precursor B)
    BNP antibody [N1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human BNP. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    NPPB (Natriuretic Peptide Precursor B (NPPB))
    Alternative Name
    natriuretic peptide B (NPPB Products)
    Synonyms
    BNP1 antibody, NPPB antibody, BNP antibody, Bnf antibody, natriuretic peptide B antibody, NPPB antibody, Nppb antibody
    Background
    This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

    Cellular Localization: Secreted
    Molecular Weight
    15 kDa
    Gene ID
    4879
    UniProt
    P16860
    Pathways
    Hormone Activity
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