NDRG1 antibody

Catalog No. ABIN2854786

Product Details anti-NDRG1 Antibody

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDRG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to NDRG1 (N-myc downstream regulated 1)
NDRG1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NDRG1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , HepG2 , NIH-3T3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.67 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NDRG1

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Alternative Name: N-myc downstream regulated 1 (NDRG1 Products)

Synonyms: CAP43 antibody, CMT4D antibody, DRG-1 antibody, DRG1 antibody, GC4 antibody, HMSNL antibody, NDR1 antibody, NMSL antibody, PROXY1 antibody, RIT42 antibody, RTP antibody, TARG1 antibody, TDD5 antibody, Ndr1 antibody, Ndrl antibody, cap43 antibody, cmt4d antibody, drg1 antibody, gc4 antibody, hmsnl antibody, ndr1 antibody, ndrg1 antibody, nmsl antibody, proxy1 antibody, rit42 antibody, rtp antibody, targ1 antibody, tdd5 antibody, xndrg1 antibody, ndrg4 antibody, cb775 antibody, wu:fb60h02 antibody, zgc:63944 antibody, NDRG1 antibody, NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN antibody, non race-specific disease resistance 1 antibody, ndrg1-a antibody, ndrg1-b antibody, xNDRG1-A antibody, ndrg1l antibody, zgc:73047 antibody, N-myc downstream regulated 1 antibody, N-myc downstream regulated gene 1 antibody, N-myc downstream regulated 1 S homeolog antibody, N-myc downstream regulated 1a antibody, Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family antibody, N-myc downstream regulated 1 L homeolog antibody, N-myc downstream regulated 1b antibody, NDRG1 antibody, Ndrg1 antibody, ndrg1.S antibody, ndrg1 antibody, ndrg1a antibody, NDR1 antibody, ndrg1.L antibody, ndrg1b antibody

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Cellular Localization: Cytoplasm , Nucleus , Cell membrane

Molecular Weight: 43 kDa

Gene ID: 10397

UniProt: Q92597