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CXCR1 antibody (C-Term)

KO Validated CXCR1 Reactivity: Human IHC (p), IF, ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854740
  • Target See all CXCR1 Antibodies
    CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
    Binding Specificity
    • 15
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 44
    • 17
    • 9
    Human
    Host
    • 41
    • 6
    • 3
    Rabbit
    Clonality
    • 42
    • 7
    • 1
    Polyclonal
    Conjugate
    • 23
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR1 antibody is un-conjugated
    Application
    • 35
    • 18
    • 13
    • 13
    • 11
    • 11
    • 9
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to CXCR1 (chemokine (C-X-C motif) receptor 1)
    CXCR1 antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CXCR1. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.97 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
    Alternative Name
    C-X-C motif chemokine receptor 1 (CXCR1 Products)
    Background
    The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

    Cellular Localization: Cell membrane
    Molecular Weight
    40 kDa
    Gene ID
    3577
    UniProt
    P25024
    Pathways
    cAMP Metabolic Process
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