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HRH4 antibody (N-Term)

KO Validated HRH4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854739
  • Target See all HRH4 Antibodies
    HRH4 (Histamine Receptor H4 (HRH4))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 60
    • 7
    • 2
    • 1
    • 1
    Human
    Host
    • 65
    • 1
    Rabbit
    Clonality
    • 65
    • 1
    Polyclonal
    Conjugate
    • 31
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HRH4 antibody is un-conjugated
    Application
    • 52
    • 31
    • 13
    • 13
    • 12
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to Histamine H4 Receptor (histamine receptor H4)
    Histamine H4 Receptor antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histamine H4 Receptor. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product HRH4 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Jurkat , Raji , NCI-H929 , human shHRH4-transfected HeLa cells

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." in: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

  • Target
    HRH4 (Histamine Receptor H4 (HRH4))
    Alternative Name
    histamine receptor H4 (HRH4 Products)
    Synonyms
    AXOR35 antibody, BG26 antibody, GPCR105 antibody, GPRv53 antibody, H4 antibody, H4R antibody, HH4R antibody, HRH4 antibody, histamine receptor H4 antibody, HRH4 antibody, Hrh4 antibody
    Background
    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors.

    Cellular Localization: Cell membrane, Multi-pass membrane protein
    Molecular Weight
    44 kDa
    Gene ID
    59340
    UniProt
    Q9H3N8
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