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EDNRB antibody (N-Term)

EDNRB Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854727
  • Target See all EDNRB Antibodies
    EDNRB (Endothelin Receptor Type B (EDNRB))
    Binding Specificity
    • 16
    • 15
    • 10
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 64
    • 33
    • 33
    • 8
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    Human
    Host
    • 76
    • 7
    • 2
    • 1
    Rabbit
    Clonality
    • 76
    • 10
    Polyclonal
    Conjugate
    • 34
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EDNRB antibody is un-conjugated
    Application
    • 64
    • 24
    • 19
    • 13
    • 13
    • 13
    • 12
    • 11
    • 9
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to ETBR (endothelin receptor type B)
    ETBR antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Endothelin B Receptor. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product EDNRB Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: A431 , H1299

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    EDNRB (Endothelin Receptor Type B (EDNRB))
    Alternative Name
    endothelin receptor type B (EDNRB Products)
    Synonyms
    ABCDS antibody, ET-B antibody, ET-BR antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, Ednra antibody, Etb antibody, ETR-b antibody, ETb antibody, Sox10m1 antibody, EDNRB antibody, abcds antibody, etb antibody, etrb antibody, hscr antibody, hscr2 antibody, endothelin receptor type B antibody, EDNRB antibody, Ednrb antibody, ednrb antibody
    Background
    The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct.

    Cellular Localization: Cell membrane
    Molecular Weight
    50 kDa
    Gene ID
    1910
    UniProt
    P24530
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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