Complement Factor H antibody
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- Target See all Complement Factor H (CFH) Antibodies
- Complement Factor H (CFH)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Complement Factor H antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human
- Characteristics
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Rabbit Polyclonal antibody to Factor H (complement factor H)
Factor H antibody [N3C1], Internal - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Factor H. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product CFH Primary Antibody
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- Application Notes
- WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: human plasma
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Complement Factor H (CFH)
- Alternative Name
- complement factor H (CFH Products)
- Synonyms
- AHUS1 antibody, AMBP1 antibody, ARMD4 antibody, ARMS1 antibody, CFHL3 antibody, FH antibody, FHL1 antibody, HF antibody, HF1 antibody, HF2 antibody, HUS antibody, Mud-1 antibody, NOM antibody, Sas-1 antibody, Sas1 antibody, Fh antibody, CFH antibody, im:7147412 antibody, si:ch211-207o17.2 antibody, fH antibody, armd4 antibody, arms1 antibody, cfh antibody, cfhl3 antibody, fhl1 antibody, hf1 antibody, hf2 antibody, hus antibody, complement factor H antibody, complement component factor h antibody, complement factor H-related protein 5 antibody, complement factor H L homeolog antibody, CFH antibody, Cfh antibody, cfh antibody, LOC100399888 antibody, LOC100733902 antibody, cfh.L antibody
- Background
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This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Secreted - Molecular Weight
- 139 kDa
- Gene ID
- 3075
- UniProt
- P08603
- Pathways
- Complement System, Cellular Response to Molecule of Bacterial Origin
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