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FOXO3 antibody (C-Term)

Name: FOXO3 antibody (C-Term)
Brand: antibodies-online
SKU: ABIN2854686
Price: 637.78 USD
Availability: InStock

KO Validated FOXO3 Reactivity: Human WB, IF, IHC (p), IP, ICC Host: Rabbit Polyclonal unconjugated

WB Image Sample (30 ug of whole cell lysate) A: 293T 7. (FOXO3 antibody (C-Term))

ICC/IF Image FOXO3A antibody [C3], C-term detects FOXO3A protein at nucleus by immunofluorescent analysis. (FOXO3 antibody (C-Term))

IP Image FOXO3A antibody immunoprecipitates FOXO3A protein in IP experiments. (FOXO3 antibody (C-Term))

WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7. (FOXO3 antibody (C-Term))

IHC-P Image Immunohistochemical analysis of paraffin-embedded Huh-7 xenograft, using FOXO3A, antibody at 1:500 dilution. (FOXO3 antibody (C-Term))

IHC

5 images

Catalog No. ABIN2854686

Datasheet as PDF

Target See all FOXO3 Antibodies

FOXO3 (Forkhead Box O3 (FOXO3))
Binding Specificity
34

12

8

8

8

8

7

7

6

6

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reactivity
128

78

69

9

7

6

5

5

4

4

3

3

2

2

2

1
Human
Host
124

5

1

1
Rabbit
Compatible Secondaries
Clonality
116

15
Polyclonal
Conjugate
67

9

6

5

5

4

4

4

4

4

4

4

1

1

1

1

1

1

1

1

1

1

1
This FOXO3 antibody is un-conjugated
Application
95

59

52

31

21

15

14

14

14

12

4

3

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Cross-Reactivity

Human, Mouse, Rat, Squirrel, Xenopus laevis

Characteristics

Rabbit Polyclonal antibody to FOXO3A (forkhead box O3)
FOXO3A antibody [C3], C-term

Purification

Purified by antigen-affinity chromatography.

Grade

KO Validated

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FOXO3A. The exact sequence is proprietary.

Isotype

IgG

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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (AA 394-672) antibody
FOXO3 Reactivity: Mouse WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (C-Term) antibody
Verified FOXO3 Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibody
FOXO3 Reactivity: Human, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (N-Term) antibody
FOXO3 Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Sheep, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) antibody
FOXO3 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Monoclonal 1E2 unconjugated Recombinant Antibody

anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibody
FOXO3 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1F6 unconjugated

anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibody
FOXO3 Reactivity: Human ELISA, IF, IHC (p) Host: Mouse Monoclonal 1E11 unconjugated

anti-Forkhead Box O3 (FOXO3) (N-Term) antibody
FOXO3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (pSer425) antibody
FOXO3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment

Positive Control: Mouse brain , C2C12
Validation: KO/KD, Orthogonal

Restrictions

For Research Use only
Format

Liquid

Concentration

0.56 mg/mL

Buffer

1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

FOXO3 (Forkhead Box O3 (FOXO3))

Alternative Name

forkhead box O3 (FOXO3 Products)

Synonyms

AF6q21 antibody, FKHRL1 antibody, FKHRL1P2 antibody, FOXO2 antibody, FOXO3A antibody, zgc:92176 antibody, wu:fb50g02 antibody, wu:fi33f07 antibody, Fkhrl1 antibody, Foxo3a antibody, FoxO3A antibody, 1110048B16Rik antibody, 2010203A17Rik antibody, C76856 antibody, Fkhr2 antibody, FOXO-3 antibody, FOXO3 antibody, foxo3a antibody, xfoxo3 antibody, foxO3 antibody, foxO antibody, fkhr antibody, foxo5 antibody, wu:fj65a12 antibody, zFkhr antibody, forkhead box O3 antibody, forkhead box O3A antibody, forkhead box O3 L homeolog antibody, forkhead box O3b antibody, FOXO3 antibody, foxo3a antibody, Foxo3 antibody, foxo3.L antibody, foxo3 antibody, foxO3 antibody, foxo3b antibody

Background

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

Cellular Localization: Cytoplasm , cytosol , Nucleus

Molecular Weight

71 kDa

Gene ID

2309

UniProt

O43524

Pathways

Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis