PLCH1 antibody

Catalog No. ABIN2854598

Product Details anti-PLCH1 Antibody

Target: PLCH1 (PLCh1) (Phospholipase C eta 1 (PLCh1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to PLCH1 (phospholipase C, eta 1)
PLCH1 antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PLCH1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.93 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-PLCH1 antibody (ABIN2854598)

Chomyk, Volsko, Tripathi, Deckard, Trapp, Fox, Dutta: "DNA methylation in demyelinated multiple sclerosis hippocampus." in: Scientific reports, Vol. 7, Issue 1, pp. 8696, (2019) (PubMed).

Target Details for PLCH1

Target: PLCH1 (PLCh1) (Phospholipase C eta 1 (PLCh1))

Alternative Name: phospholipase C eta 1 (PLCh1 Products)

Synonyms: PLCL3 antibody, BC042549 antibody, PLCeta1 antibody, Plcl3 antibody, RGD1561991 antibody, phospholipase C eta 1 antibody, phospholipase C, eta 1 antibody, PLCH1 antibody, Plch1 antibody

Background: PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM]

Cellular Localization: Cytoplasm , Membrane

Molecular Weight: 189 kDa

Gene ID: 23007

UniProt: Q4KWH8