DOK3 antibody (C-Term)

Catalog No. ABIN2854590

Product Details anti-DOK3 Antibody

Target: DOK3 (Docking Protein 3 (DOK3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Docking protein 3 (docking protein 3)
Docking protein 3 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DOK3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DOK3

Target: DOK3 (Docking Protein 3 (DOK3))

Alternative Name: docking protein 3 (DOK3 Products)

Synonyms: DOK3 antibody, DOKL antibody, AI450713 antibody, Dokl antibody, docking protein 3 antibody, DOK3 antibody, Dok3 antibody

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function.

Cellular Localization: Cytoplasm , Cell membrane, Peripheral membrane protein, Cytoplasmic side , Cytoplasm , Cell membrane

Molecular Weight: 53 kDa

Gene ID: 79930

UniProt: Q7L591