PPOX antibody

Catalog No. ABIN2854549

Product Details anti-PPOX Antibody

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPOX antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to PPOX (protoporphyrinogen oxidase)
PPOX antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PPOX. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549 , HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.82 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PPOX

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Alternative Name: protoporphyrinogen oxidase (PPOX Products)

Synonyms: PPO antibody, V290M antibody, VP antibody, Ppo antibody, BcDNA:LD41392 antibody, CG5796 antibody, Dmel\\CG5796 antibody, ESTS:9F2T antibody, zgc:123252 antibody, HEMG1 antibody, PPO1 antibody, PROTOPORPHYRINOGEN OXIDASE antibody, TC0121 antibody, hemG antibody, protoporphyrinogen oxidase antibody, Protoporphyrinogen oxidase antibody, Flavin containing amine oxidoreductase family antibody, polyphenol oxidase, chloroplastic antibody, PPOX antibody, Ppox antibody, ppox antibody, hemY antibody, TC_RS00645 antibody, Mrub_1406 antibody, Mesil_2992 antibody, Trad_0583 antibody, Calni_0746 antibody, Ocepr_1049 antibody, Tmar_0766 antibody, Intca_1907 antibody, Despr_0642 antibody, Plabr_2407 antibody, Deipr_2130 antibody, Hipma_0622 antibody, LOC110782963 antibody

Background: This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Cellular Localization: Mitochondrion inner membrane, Peripheral membrane protein, Intermembrane side

Molecular Weight: 51 kDa

Gene ID: 5498

UniProt: P50336

Pathways: Synaptic Membrane, Feeding Behaviour