NKRF antibody

Catalog No. ABIN2854512

Product Details anti-NKRF Antibody

Target: NKRF (NFKB Repressing Factor (NKRF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKRF antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to NKRF (NFKB repressing factor)
NKRF antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NKRF. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-NKRF antibody (ABIN2854512)

Alexandrova, Piñeiro, Jukes-Jones, Mordue, Stoneley, Willis: "Full-length NF-κB repressing factor contains an XRN2 binding domain." in: The Biochemical journal, Vol. 477, Issue 4, pp. 773-786, (2020) (PubMed).

Target Details for NKRF

Target: NKRF (NFKB Repressing Factor (NKRF))

Alternative Name: NFKB repressing factor (NKRF Products)

Background: This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.

Cellular Localization: Nucleus , nucleolus

Molecular Weight: 78 kDa

Gene ID: 55922

UniProt: O15226