PLCL1 antibody (N-Term)

Catalog No. ABIN2854504

Product Details anti-PLCL1 Antibody

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCL1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Rhesus Monkey

Cross-Reactivity (Details): Rhesus Monkey (100 %)

Characteristics: Rabbit polyclonal antibody to PLCL1 (phospholipase C-like 1)
PLCL1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human PLCL1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*

Comment:

Positive Control: Target recombinant protein

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.92 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PLCL1

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Alternative Name: PLCL1 (PLCL1 Products)

Synonyms: PLCE antibody, PLCL antibody, PLDL1 antibody, PRIP antibody, C230017K02Rik antibody, PLC-L antibody, PLC-L1 antibody, PRIP-1 antibody, phospholipase C like 1 (inactive) antibody, phospholipase C-like 1 antibody, PLCL1 antibody, Plcl1 antibody

Background: Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.

Cellular Localization: Cytoplasm

Molecular Weight: 123 kDa

Gene ID: 5334