ACOT8 antibody
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- Target See all ACOT8 Antibodies
- ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ACOT8 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
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Rabbit polyclonal antibody to ACOT8 (acyl-CoA thioesterase 8)
ACOT8 antibody [N1C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ACOT8. The exact sequence is proprietary.
- Isotype
- IgG
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: Molt-4 , Raji , 293T , HepG2 , mouse liver , rat liver
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))
- Alternative Name
- acyl-CoA thioesterase 8 (ACOT8 Products)
- Synonyms
- PTE1 antibody, zgc:101691 antibody, HNAACTE antibody, PTE-1 antibody, PTE-2 antibody, PTE2 antibody, hACTE-III antibody, hTE antibody, Pte1 antibody, acyl-CoA thioesterase 8 antibody, ACOT8 antibody, acot8 antibody, Acot8 antibody
- Background
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The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene.
Cellular Localization: Peroxisome - Molecular Weight
- 36 kDa
- Gene ID
- 10005
- UniProt
- O14734
- Pathways
- Monocarboxylic Acid Catabolic Process
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