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ENPP1 antibody

KO Validated ENPP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854438
  • Target See all ENPP1 Antibodies
    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
    Reactivity
    • 42
    • 35
    • 11
    • 7
    • 4
    Human
    Host
    • 74
    • 5
    • 2
    Rabbit
    Clonality
    • 78
    • 3
    Polyclonal
    Conjugate
    • 21
    • 13
    • 12
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ENPP1 antibody is un-conjugated
    Application
    • 66
    • 35
    • 14
    • 14
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1)
    ENPP1 antibody [N2C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human ENPP1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ENPP1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HepG2 , human liver

    Validation: KO/KD, Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.14 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Huang, Chang, Kuo, Chen, Jeng, Chang, Shew, Hu, Lee: "Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate." in: Nature communications, Vol. 8, pp. 14706, (2018) (PubMed).

  • Target
    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
    Alternative Name
    ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1 Products)
    Synonyms
    ENPP1 antibody, si:ch211-142e24.2 antibody, zgc:136238 antibody, ARHR2 antibody, M6S1 antibody, NPP1 antibody, NPPS antibody, PC-1 antibody, PCA1 antibody, PDNP1 antibody, 4833416E15Rik antibody, AI428932 antibody, C76301 antibody, CD203c antibody, E-NPP1 antibody, Ly-41 antibody, Npps antibody, Pca antibody, Pca-1 antibody, Pdnp1 antibody, ttw antibody, twy antibody, Pc1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 L homeolog antibody, ENPP1 antibody, enpp1 antibody, enpp1.L antibody, Enpp1 antibody
    Background
    This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

    Molecular Weight
    105 kDa
    Gene ID
    5167
    UniProt
    P22413
    Pathways
    Regulation of Carbohydrate Metabolic Process
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