CLTA antibody

Catalog No. ABIN2854366

Product Details anti-CLTA Antibody

Target: CLTA (Clathrin, Light Chain A (CLTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLTA antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to CLTA (clathrin, light chain (Lca))
CLTA antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CLTA. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549 , mouse brain , rat brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CLTA

Target: CLTA (Clathrin, Light Chain A (CLTA))

Alternative Name: clathrin light chain A (CLTA Products)

Synonyms: lca antibody, zgc:73358 antibody, wu:fb61d08 antibody, wu:fj48d06 antibody, CLTA antibody, DDBDRAFT_0169251 antibody, DDBDRAFT_0191305 antibody, DDB_0169251 antibody, DDB_0191305 antibody, clc antibody, LCA antibody, LCA1 antibody, LCA2 antibody, LCA3 antibody, CLTA2 antibody, AV026556 antibody, Clathrin light chain antibody, clathrin light chain A antibody, clathrin, light chain A antibody, clathrin, light chain (Lca) antibody, clathrin light chain antibody, clathrin, light polypeptide (Lca) antibody, clic-1 antibody, clta antibody, CLTA antibody, CNI00580 antibody, LOC5567495 antibody, CLC1 antibody, CpipJ_CPIJ018056 antibody, PTRG_01988 antibody, PMAA_096950 antibody, SJAG_04517 antibody, TSTA_044110 antibody, PAS_chr1-4_0158 antibody, clc antibody, Clta antibody

Background: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.

Cellular Localization: Cytoplasmic vesicle membrane , Membrane , coated pit

Molecular Weight: 27 kDa

Gene ID: 1211

UniProt: P09496

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation