EXT2 antibody (Internal Region)

Catalog No. ABIN2854365

Product Details anti-EXT2 Antibody

Target: EXT2 (Exostosin 2 (EXT2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXT2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio), Cow (Bovine), Xenopus tropicalis

Cross-Reactivity (Details): Mouse (98 %), Rat (96 %), Xenopus laevis (88 %), Zebrafish (84 %), Bovine (97 %), Xenopus tropicalis (89 %)

Characteristics: Rabbit polyclonal antibody to EXT2 (exostoses (multiple) 2)
EXT2 antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human EXT2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: A549 , HeLa , Jurkat , NT2D1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.57 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for EXT2

Target: EXT2 (Exostosin 2 (EXT2))

Alternative Name: Exostosin 2 (EXT2 Products)

Synonyms: SOTV antibody, AI893565 antibody, EXT2 antibody, ext2 antibody, exostosin glycosyltransferase 2 antibody, exostoses (multiple) 2 antibody, exostoses (multiple) 3 antibody, exostosin glycosyltransferase 2 L homeolog antibody, EXT2 antibody, Ext2 antibody, EXT3 antibody, ext2.L antibody

Background: This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Cellular Localization: Endoplasmic reticulum membrane, Single-pass type II membrane protein , Golgi apparatus membrane, Single-pass type II membrane protein

Molecular Weight: 82 kDa

Gene ID: 2132

Pathways: Glycosaminoglycan Metabolic Process