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Chitotriosidase 1 antibody

CHIT1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854344
  • Target See all Chitotriosidase 1 (CHIT1) Antibodies
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    Reactivity
    • 31
    • 5
    • 2
    Human
    Host
    • 22
    • 10
    • 1
    Rabbit
    Clonality
    • 25
    • 8
    Polyclonal
    Conjugate
    • 22
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chitotriosidase 1 antibody is un-conjugated
    Application
    • 19
    • 13
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to Chitotriosidase (chitinase 1 (chitotriosidase))
    Chitotriosidase antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human CHIT1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product CHIT1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    Alternative Name
    chitinase 1 (CHIT1 Products)
    Background
    Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

    Cellular Localization: Secreted , Lysosome
    Molecular Weight
    52 kDa
    Gene ID
    1118
    UniProt
    Q13231
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