BLM antibody (N-Term)

Catalog No. ABIN2854325

Product Details anti-BLM Antibody

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLM antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Characteristics: Rabbit Polyclonal antibody to BLM (Bloom syndrome, RecQ helicase-like)
BLM antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human BLM. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: Jurkat , Raji , NCI-H929

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.93 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for BLM

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Alternative Name: BLM (BLM Products)

Synonyms: BS antibody, RECQ2 antibody, RECQL2 antibody, RECQL3 antibody, blm-A antibody, xBLM antibody, ORF1 antibody, Bloom syndrome RecQ like helicase antibody, Bloom syndrome RecQ like helicase S homeolog antibody, Bloom syndrome, RecQ like helicase antibody, BLM antibody, blm.S antibody, Blm antibody

Background: The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.

Cellular Localization: Nucleus

Molecular Weight: 159 kDa

Gene ID: 641

Pathways: DNA Damage Repair