RAD54L antibody (N-Term)

Catalog No. ABIN2854291

Product Details anti-RAD54L Antibody

Target: RAD54L (RAD54-Like (RAD54L))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD54L antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (90 %)

Characteristics: Rabbit polyclonal antibody to RAD54L (RAD54-like (S. cerevisiae))
RAD54L antibody [N1N2-2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human RAD54L. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.55 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RAD54L

Target: RAD54L (RAD54-Like (RAD54L))

Alternative Name: RAD54L (RAD54L Products)

Synonyms: HR54 antibody, RAD54A antibody, hHR54 antibody, hRAD54 antibody, RAD54 antibody, zgc:56289 antibody, rad54l antibody, MGC69368 antibody, GdRAD54 antibody, RAD54-like antibody, RAD54L antibody, RAD54 like antibody, RAD54 like (S. cerevisiae) antibody, RAD54-like (S. cerevisiae) antibody, RAD54L antibody, Rad54l antibody, rad54l antibody

Background: The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.

Cellular Localization: Nucleus

Molecular Weight: 84 kDa

Gene ID: 8438

Pathways: DNA Damage Repair