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POLE3 antibody

POLE3 Reactivity: Human, Mouse, Monkey WB, IF, IP, ICC Host: Mouse Monoclonal 3C5-1 unconjugated
Catalog No. ABIN363202
  • Target See all POLE3 Antibodies
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Reactivity
    • 39
    • 19
    • 16
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Monkey
    Host
    • 34
    • 5
    Mouse
    Clonality
    • 37
    • 2
    Monoclonal
    Conjugate
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This POLE3 antibody is un-conjugated
    Application
    • 22
    • 9
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificity
    Reacts with DNA polymerase epsilon from human mouse, monkey, mink and hamster
    Cross-Reactivity (Details)
    Does not recognize DNA pol alpha, beta or delta. Does not reacts with Drosophilia or baculovirus host cell pol epsilon, and weakly, if at all, on S. cerivisae pol epsilon.
    Purification
    Purified (protein G)
    Immunogen
    Human DNA Polymerase epsilon purified from HeLa cells
    Clone
    3C5-1
    Isotype
    IgG2a
    Top Product
    Discover our top product POLE3 Primary Antibody
  • Application Notes

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    ICC/IF1:100, IP1:10-1:500, WB5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    16 mg/mL
    Buffer
    PBS
    Storage
    -20 °C/-80 °C
    Storage Comment
    Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
  • Target
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Alternative Name
    DNA Polymerase epsilon Subunit 3 (POLE3 Products)
    Synonyms
    NCU04548.1 antibody, GB14966 antibody, zgc:73351 antibody, 1810034K18Rik antibody, YBL1 antibody, CHARAC17 antibody, CHRAC17 antibody, p17 antibody, DNA polymerase epsilon 3, accessory subunit antibody, polymerase (DNA directed), epsilon 3, accessory subunit antibody, DNA polymerase epsilon antibody, DNA polymerase epsilon p17 subunit antibody, DNA polymerase epsilon subunit 3 antibody, polymerase (DNA directed), epsilon 3 (p17 subunit) antibody, POLE3 antibody, pole3 antibody, NCU04548 antibody, CpipJ_CPIJ008666 antibody, Bm1_04865 antibody, Bm1_07285 antibody, CTRG_00708 antibody, LOAG_09571 antibody, LOC726923 antibody, Pole3 antibody
    Background
    Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
    Gene ID
    54107
    UniProt
    Q9NRF9
    Pathways
    DNA Damage Repair
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