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EGF antibody (Center)

EGF Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB16555 unconjugated
Catalog No. ABIN656805
  • Target See all EGF Antibodies
    EGF (Epidermal Growth Factor (EGF))
    Binding Specificity
    • 45
    • 16
    • 10
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 690-720, Center
    Reactivity
    • 152
    • 87
    • 47
    • 12
    • 11
    • 5
    • 4
    • 1
    • 1
    Human, Mouse
    Host
    • 215
    • 31
    • 10
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 221
    • 39
    Polyclonal
    Conjugate
    • 111
    • 34
    • 20
    • 16
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This EGF antibody is un-conjugated
    Application
    • 200
    • 92
    • 63
    • 53
    • 53
    • 28
    • 25
    • 23
    • 16
    • 16
    • 15
    • 13
    • 10
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 689-720 amino acids from the Central region of human EGF.
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-720 AA from the Central region of human EGF.
    Clone
    RB16555
    Isotype
    Ig Fraction
    Top Product
    Discover our top product EGF Primary Antibody
  • Application Notes
    WB = 1:1000, IHC (p) = 1:10-50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    EGF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    EGF (Epidermal Growth Factor (EGF))
    Alternative Name
    EGF (EGF Products)
    Synonyms
    HOMG4 antibody, URG antibody, AI790464 antibody, CEGF antibody, epidermal growth factor antibody, pro-epidermal growth factor antibody, EGF antibody, egf antibody, CpipJ_CPIJ020278 antibody, Egf antibody
    Background
    This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
    Synonyms: Pro-epidermal growth factor,EGF,
    Molecular Weight
    133994 DA
    Gene ID
    1950
    NCBI Accession
    NP_001954
    UniProt
    P01133
    Pathways
    NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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