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BCL3 antibody (Center)

BCL3 Reactivity: Human, Mouse WB, FACS, IF, IHC (p) Host: Rabbit Polyclonal RB23954 unconjugated
Catalog No. ABIN653286
  • Target See all BCL3 Antibodies
    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 249-277, Center
    Reactivity
    • 41
    • 35
    • 2
    Human, Mouse
    Host
    • 48
    • 8
    • 5
    Rabbit
    Clonality
    • 50
    • 11
    Polyclonal
    Conjugate
    • 25
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL3 antibody is un-conjugated
    Application
    • 39
    • 15
    • 13
    • 13
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248~277 amino acids from the Center region of human BCL3.
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 AA from the Central region of human BCL3.
    Clone
    RB23954
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BCL3 Primary Antibody
  • Application Notes
    WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.48 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Gehrke, Wörns, Huber, Hess, Straub, Hövelmeyer, Waisman, Kim, Schuppan, Galle, Schattenberg: "Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors." in: Journal of hepatology, Vol. 65, Issue 6, pp. 1188-1197, (2018) (PubMed).

  • Target
    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
    Alternative Name
    BCL3 (BCL3 Products)
    Synonyms
    BCL3 antibody, AI528691 antibody, Bcl-3 antibody, BCL4 antibody, D19S37 antibody, B-cell CLL/lymphoma 3 antibody, B cell leukemia/lymphoma 3 antibody, BCL3 antibody, Bcl3 antibody
    Background
    BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
    Synonyms: Proto-oncogene BCL3, B-cell lymphoma 3 protein, BCL-3, D19S37, BCL4, BCL3
    Molecular Weight
    46800 Da
    Gene ID
    602
    UniProt
    P20749
    Pathways
    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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