Recombinant PEG antibody (methoxylated)

Catalog No. ABIN2830995

Product Details anti-PEG Antibody

Target: PEG (Polyethylene Glycol (PEG))

Antibody Type: Recombinant Antibody

Binding Specificity: methoxylated

Reactivity: All Species

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PEG antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Specificity: This antibody reacts to lysine-acetylated proteins.

Cross-Reactivity (Details): No cross reactivity with nonacetylated lysine, and lysine with other modification.

Purification: Protein A affinity purified from an animal origin-free culture supernatant

Immunogen: KLH-PEG with terminal methoxy group

Clone: RM105

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12-24 months

References for anti-PEG antibody (ABIN2830995)

Lam, Yan, Xu, U, Cheng, Ho: "Endogenous arginase 2 as a potential biomarker for PEGylated arginase 1 treatment in xenograft models of squamous cell lung carcinoma." in: Oncogenesis, Vol. 8, Issue 3, pp. 18, (2019) (PubMed).

Lam, Li, Xu, Leung, U, Zheng, Cheng, Ho: "Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts." in: Respiratory research, Vol. 18, Issue 1, pp. 80, (2018) (PubMed).

Lam, U, Li, Xu, Cheng, Ho: "Inhibition of ornithine decarboxylase 1 facilitates pegylated arginase treatment in lung adenocarcinoma xenograft models." in: Oncology reports, Vol. 40, Issue 4, pp. 1994-2004, (2018) (PubMed).

Xu, Lam, Cheng, Ho: "Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer." in: Cancer science, Vol. 109, Issue 11, pp. 3471-3482, (2018) (PubMed).

McCallen, Prybylski, Yang, Lai: "Cross-Reactivity of Select PEG-Binding Antibodies to Other Polymers Containing a C-C-O Backbone." in: ACS biomaterials science & engineering, Vol. 3, Issue 8, pp. 1605-1615, (2017) (PubMed).

Target Details for PEG

Target: PEG (Polyethylene Glycol (PEG))

Alternative Name: PEG (Methoxy Group) (PEG Products)