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HEXDC antibody (AA 1-100) (AbBy Fluor® 594)

HEXDC Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 594
Catalog No. ABIN2814311
  • Target See all HEXDC Antibodies
    HEXDC (Hexosaminidase D (HEXDC))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    AA 1-100
    Reactivity
    • 19
    • 1
    • 1
    Human
    Host
    • 17
    • 2
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HEXDC antibody is conjugated to AbBy Fluor® 594
    Application
    • 19
    • 12
    • 12
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HEXDC
    Isotype
    IgG
    Top Product
    Discover our top product HEXDC Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HEXDC (Hexosaminidase D (HEXDC))
    Alternative Name
    HEXDC (HEXDC Products)
    Synonyms
    BC069960 antibody, fj33c04 antibody, wu:fj33c04 antibody, zgc:152869 antibody, hexdc antibody, hexosaminidase D antibody, hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing antibody, hexosaminidase D L homeolog antibody, HEXDC antibody, Hexdc antibody, hexdc antibody, hexdc.L antibody
    Background

    Synonyms: Beta hexosaminidase D, Beta N acetylhexosaminidase, FLJ23825, Hexosaminidase glycosyl hydrolase family 20 catalytic domain containing, hexosaminidase glycosyl hydrolase family 20, catalytic domain, Hexosaminidase D, Hexosaminidase domain containing protein, N acetyl beta galactosaminidase, HEXDC_HUMAN.

    Background: HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    Gene ID
    284004
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