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G6PC antibody (AbBy Fluor® 594)

G6PC Reactivity: Human, Mouse, Rat, Dog, Cow, Pig WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 594
Catalog No. ABIN2813809
  • Target See all G6PC Antibodies
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    Reactivity
    • 42
    • 21
    • 20
    • 15
    • 13
    • 12
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Pig
    Host
    • 42
    • 1
    Rabbit
    Clonality
    • 42
    • 1
    Polyclonal
    Conjugate
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This G6PC antibody is conjugated to AbBy Fluor® 594
    Application
    • 30
    • 19
    • 15
    • 11
    • 10
    • 4
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Cow, Dog, Human, Mouse, Pig, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha
    Isotype
    IgG
    Top Product
    Discover our top product G6PC Primary Antibody
  • Application Notes
    IF(IHC-P)(1:50-200)
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    Alternative Name
    Glucose 6 Phosphatase alpha (G6PC Products)
    Synonyms
    AW107337 antibody, G6Pase antibody, G6pt antibody, Glc-6-Pase antibody, G6PC1 antibody, G6PT antibody, GSD1 antibody, GSD1a antibody, G-6-Pase antibody, glucose-6-phosphatase, catalytic antibody, glucose-6-phosphatase catalytic subunit antibody, glucose-6-phosphatase, catalytic subunit antibody, G6pc antibody, G6PC antibody
    Background

    Synonyms: glucose-6-phosphatase, catalytic subunit, GSD1, AW107337, G-6-Pase, G6Pase, G6Pase-alpha, g6pc, G6PC_HUMAN, G6PT, Glucose-6-phosphatase alpha, Glucose-6-phosphatase, GSD1a, MGC163350, MGC93613, RP23-281C18.19.

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-i±, a second form, designated G6Pase-i², contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-i², also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-i² hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-i² may play an integral role in diabetes and glycogen storage diseases (GSDs).

    Gene ID
    2538
    Pathways
    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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