GCHFR antibody (AA 21-60) (AbBy Fluor® 594)
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- Target See all GCHFR Antibodies
- GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))
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Binding Specificity
- AA 21-60
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GCHFR antibody is conjugated to AbBy Fluor® 594
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Cow,Pig,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GCHFR
- Isotype
- IgG
- Top Product
- Discover our top product GCHFR Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))
- Alternative Name
- GCHFR (GCHFR Products)
- Synonyms
- GFRP antibody, HsT16933 antibody, P35 antibody, 2010323F13Rik antibody, GTP cyclohydrolase I feedback regulator antibody, GCHFR antibody, Gchfr antibody
- Background
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Synonyms: GCHFR, GFRP, GFRP_HUMAN, GTP cyclohydrolase 1 feedback regulatory protein, GTP cyclohydrolase I feedback regulator, GTP cyclohydrolase I feedback regulatory protein, HsT16933, MGC138467, MGC138469, p35.
Background: GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. The molecular weight of GFRP is approximately 9.5 kDa although cross-linking experiments have shown that GFRP is usually found as a homodimer or as a pentamer. 15q15.
- Gene ID
- 2644
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