CTDSPL antibody (AA 175-276) (AbBy Fluor® 594)

Catalog No. ABIN2812029

Product Details anti-CTDSPL Antibody (AbBy Fluor® 594)

Target: CTDSPL (CTD Small Phosphatase-Like Protein (CTDSPL))

Binding Specificity: AA 175-276

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTDSPL antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTDSPL

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CTDSPL

Target: CTDSPL (CTD Small Phosphatase-Like Protein (CTDSPL))

Alternative Name: CTDSPL (CTDSPL Products)

Synonyms: C3orf8 antibody, HYA22 antibody, PSR1 antibody, RBSP3 antibody, SCP3 antibody, 2810418J22Rik antibody, AI426263 antibody, NFI1 antibody, NIF antibody, XNIF antibody, ctdspl antibody, ctdspl.L antibody, nif antibody, scp3 antibody, CTD small phosphatase like antibody, TIM23 translocase complex subunit Tim50 antibody, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like antibody, CTD small phosphatase like S homeolog antibody, CTDSPL antibody, SJAG_03560 antibody, Ctdspl antibody, ctdspl.S antibody

Background:

Synonyms: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, CTD small phosphatase-like protein, CTDSL_HUMAN, CTDSP-like, Ctdspl, hYA22, N-like protein, NLI-interacting factor 1, Nuclear LIM interactor-interacting factor 1, Protein YA22, RBSP3, SCP3, Small C-terminal domain phosphatase 3, Small CTD phosphatase 3.

Background: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Gene ID: 10217