BSPRY antibody (AA 251-350) (AbBy Fluor® 594)
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- Target See all BSPRY Antibodies
- BSPRY (B-Box and SPRY Domain Containing (BSPRY))
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Binding Specificity
- AA 251-350
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BSPRY antibody is conjugated to AbBy Fluor® 594
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human BSPRY
- Isotype
- IgG
- Top Product
- Discover our top product BSPRY Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- BSPRY (B-Box and SPRY Domain Containing (BSPRY))
- Alternative Name
- BSPRY (BSPRY Products)
- Synonyms
- B-box and SPRY domain containing antibody, BSPRY antibody, Bspry antibody
- Background
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Synonyms: B box and SPRY domain containing, B box and SPRY domain containing protein, B box and SPRY domain-containing protein,B-box and SPRY domain containing, Bspry, BSPRY_HUMAN, FLJ20150, Zetin 1.
Background: BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
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