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UFD1L antibody (AbBy Fluor® 594)

UFD1L Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 594
Catalog No. ABIN2807379
  • Target See all UFD1L Antibodies
    UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
    Reactivity
    • 44
    • 31
    • 30
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 39
    • 4
    Rabbit
    Clonality
    • 39
    • 5
    Polyclonal
    Conjugate
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UFD1L antibody is conjugated to AbBy Fluor® 594
    Application
    • 36
    • 12
    • 10
    • 9
    • 7
    • 6
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UFD1L
    Isotype
    IgG
    Top Product
    Discover our top product UFD1L Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
    Alternative Name
    UFD1L (UFD1L Products)
    Synonyms
    UFD1 antibody, Ufd1 antibody, ufd1 antibody, wu:fc55f04 antibody, zgc:92341 antibody, Ufd1l antibody, ubiquitin recognition factor in ER associated degradation 1 antibody, ubiquitin recognition factor in ER-associated degradation 1 antibody, ubiquitin fusion degradation 1 like (yeast) antibody, ubiquitin recognition factor in ER associated degradation 1 S homeolog antibody, ubiquitin fusion degradation protein 1 homolog antibody, Ubiquitin Fusion Degradation (yeast UFD homolog) antibody, UFD1 antibody, Ufd1 antibody, UFD1L antibody, ufd1.S antibody, ufd1l antibody, ufd1 antibody, EHI_125920 antibody, LOC100166745 antibody, LOC100635687 antibody, LOC100648660 antibody, ufd-1 antibody
    Background

    Synonyms: UB fusion protein 1, Ubiquitin fusion degradation 1 like yeast, Ubiquitin fusion degradation 1 like, Ubiquitin fusion degradation protein 1 homolog, UFD1, UFD1L.

    Background: UFD1L is a member of the UFD1 family of proteins and is a component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. This complex, also containing UFD1L, VCP and NPLOC4, binds ubiquitinated proteins and is required for the export of misfolded proteins from the ER to the cytoplasm for disposal. The NPLOC4-UFD1L-VCP complex also regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. UFD1L gene hemizygosity is the cause of some developmental defects including DiGeorge syndrome (DGS), velo-cardio-facial syndrome (VCFS) and Opitz G/BBB syndrome. UFD1L has 2 named isoforms produced by alternative splicing.

    Gene ID
    7353
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